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Solubility of gemcitabine hydrochloride

WebApplication. It is intended to be used as a USP reference standard in specified quality tests and assays. Also used to prepare standard solutions in the assay and impurities analysis … WebGemcitabine, HCl - CAS 122111-03-9 - Calbiochem. View Price and Availability. Supelco. PHR2582. Gemcitabine hydrochloride. Pharmaceutical Secondary Standard; Certified …

Physical and Chemical Stability of Gemcitabine …

WebMar 1, 2024 · One vial contains Gemcitabine hydrochloride equivalent to 200 mg Gemcitabine One vial contains Gemcitabine hydrochloride equivalent to 1000 mg Gemcitabine . After reconstitution, the solution contains 38 mg/ml of Gemcitabine. Excipients: Each 200 mg vial contains 3.5 mg (<1 mmol) sodium. Each 1,000 mg vial … WebBiological Activity for Gemcitabine hydrochloride. Gemcitabine hydrochloride is a deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine … greenday upvc https://royalkeysllc.org

US Patent Application for COMPOSITION AND METHOD TO …

WebDec 2, 2013 · The release behavior of another anti-cancer drug gemcitabine from the PU matrix is quite different from that of PTX due to the extreme difference in water solubility between gemcitabine and PTX.PTX is practically insoluble in water, whereas gemcitabine is readily soluble in water and has a solubility of 1.55% [37,67]. WebGemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. … WebFeb 25, 2024 · The solution was then diluted 10× with a premade PBS solution of gemcitabine (hydrochloride salt) (12.65 mg/mL). Final concentrations of drugs were 10/1 mg/mL GT. CrEL drug suspensions were used within the same day of preparation due to instability. ... Whether a water soluble gemcitabine (Log P=−1.5) and insoluble paclitaxel ... fl studio 22 download free

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Solubility of gemcitabine hydrochloride

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http://shiji.cnreagent.com/s/sv273316.html WebGemcitabine hydrochloride is a deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate ...

Solubility of gemcitabine hydrochloride

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WebGemcitabine HCl (Gemzar) ... *&lt;1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and … WebNov 25, 2024 · The empirical formula for gemcitabine HCl is C 9 H 11 F 2 N 3 O 4 • HCl. It has a molecular weight of 299.66. Gemcitabine HCl is soluble in water, slightly soluble in …

WebGemcitabine Hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. … WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); &gt;= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used …

WebGemcitabine is a chemotherapeutic agent used as monotherapy or in combination with other anticancer agents. In combination with [carboplatin], it is indicated for the treatment … WebApr 1, 1999 · Gemcitabine is a fluoro-cytidine analog with primarily antitumor activity and is administered intravenously [120]. Although its hydrochloride salt is well soluble in water …

WebApr 1, 1999 · Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored …

WebGeneral description. A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties. Shown to be effective against a variety of tumors … fl studio 32 bits crackeadoWebSolubility: Soluble in DMSO at 12.5 mg/mL with slight warming; very poorly soluble in ethanol; soluble in water at 25 mg/mL with slight warming; buffers, ... Gemcitabine … fl studio 4 freeWebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, … fl studio 32 downloadWebUse in Cancer. Gemcitabine hydrochloride is approved to be used alone or with other drugs to treat: Breast cancer that cannot be treated with or that did not respond to … fl studio 3 on 3 beatWebGemcitabine Hydrochloride, CAS: 122111-03-9, is a deoxycytidine analog that inhibits ribonucleotide reductase & induces apoptosis. ... Gemcitabine Hydrochloride, sc-204763, … fl studio 9.0 free downloadWebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, USP is a sterile white to off-white lyophilized powder and available as 200 mg and 1 g single-dose vials for intravenous use only. fl studio 5 min beatgreenday upvc companies house