WebIn-vitro and in-vivo metabolic studies of the candidate chemopreventative pentamethylchromanol using liquid chromatography/tandem mass spectrometry. Gregory S Gorman, Lori Coward, Corenna Kerstner-Wood, Lea Freeman, ... WebPentamethylchromanol: Derivative IUPAC Name: Not Available: Derivative SMILES: Not Available: Derivative InChIKey: Not Available: Spectrum Type: Predicted GC-MS Spectrum - Pentamethylchromanol GC-MS (Non-derivatized) - 70eV, Positive: Splash Key: Not Available: Notes: This is a predicted spectrum, and it should only be used as a guide. Further ...
(PDF) Toxicogenomics and Metabolomics of …
Web6. dec 2009 · Toxicogenomics and metabolomics of pentamethylchromanol (PMCol)-induced hepatotoxicity. Parman T, Bunin DI, Ng HH, McDunn JE, Wulff JE, Wang A, Swezey R, Rasay L, Fairchild DG, Kapetanovic IM, Green CE. Toxicol Sci, 124(2):487-501, 13 Sep 2011 Web13. sep 2011 · Pentamethylchromanol (2,2,5,7,8-Pentamethyl-6-chromanol, PMCol), an off-white solid, was supplied by Division of Cancer Prevention Repository c/o Fisher BioServices (Germantown, MD) and refrigerated. The purity was determined by high performance liquid chromatography (HPLC) before initiation of dosing and after completion of the in-life … garfield hawaiian shirt
2,2,5,7,8-Pentamethyl-6-chromanol C14H20O2 - PubChem
WebLiver Plasma Kidney Urine Positive ion mode PMCol (parent drug) 220 0 √ √ √ √ Dehydrogenated (2) 219 −2 √ √ WebAldrich- 430676 Page 7 of 9 The life science business of Merck operates as MilliporeSigma in the US and Canada 11.2 Additional Information WebPentamethylchromanol is susceptible to multiple metabolic pathways and differential metabolic stability, which is species dependent. Conclusions: In-vitro metabolism was not a strong predictor of in-vivo metabolism for the samples assays but showed glucuronidation and sulfation as common biotransformation pathways. garfield health care center