Web31 mar. 2024 · Monoclonal serum free light chains (sFLC) are a well-known cause of renal impairment (RI) in patients with multiple myeloma (MM). As an indicator of monoclonality, sFLC ratio has acquired a key role in the diagnosis and monitorization of the disease. However, its interpretation is altered in patients with chronic kidney disease (CKD). Web30 mar. 2024 · Donati G, Moretti MI, Baraldi O, Spazzoli A, Capelli I, Comai G, Marchetti A, Sarma M, Mancini R, La Manna G. Removal of free light chains in hemodialysis …
Light-Chain Multiple Myeloma: A Diagnostic Challenge - PubMed
Web15 aug. 2024 · Light chain multiple myeloma (LCMM) constitutes approximately 15% of patients with multiple myeloma (MM). It has a poorer prognosis when compared to immunoglobulin (Ig) G or IgA variant. We performed a comprehensive literature search on LCMM and identified a total of 390 articles. Web13 aug. 2024 · In general, extremely high serum free light chains indicate refractory disease while minimal elevation at baseline and normalization after chemotherapy is considered … largest solar system in the universe
Responses in multiple myeloma should be assigned according to …
Web1 nov. 2024 · We examined the correlations of serum free light chain concentrations in light chain myelomas with survival, estimated glomerular filtration rate (eGFR) and … WebThe serum free light chain assay (Freelite®) and the serum heavy/light chain assay (Hevylite®) are two tests used in the diagnosis and monitoring of myeloma. Since … Web1 iun. 2009 · The serum free light chain assays have been fully integrated into the International Uniform Response Criteria in multiple myeloma and also into the hematologic response criteria in AL amyloidosis . 7, 23, 24 Serial monitoring with serum free light chain analysis during chemotherapy enables a real-time evaluation of tumor kill due to the short ... largest so cal ford dealership